Three well-known medications can prevent heart attack and stroke in high risk patients?

Did you know…

A study of more than 120,000 diabetes and heart disease patients conducted by Kaiser Permanente discovered that they could lower their risk of heart attack or stroke by as much as 80 percent by taking a certain combination of drugs.

Dr. R. James Dudl and his team investigated the combination of a generic statin (lovastatin), a generic blood pressure pill (lisinopril) and low-dose aspirin for patients with a history of heart disease or diabetes.  People with diabetes are two to four times more likely to get a heart attack than people without diabetes, according to the American Diabetes Association.  Similarly, people who have had a heart attack are at high risk of having a second heart attack or a stroke.  In Dr. Dudl’s study, people who took these medications regularly reduced their risk of heart attack or stroke by as much as 80 percent.  Even people who took the medications less than half the time had a 60 percent lower rate of heart attack and stroke.

The medications studied have been marketed for more than 10 years, are available in generic form, and are all considered very safe and effective.  They were prescribed at relatively low doses: a statin at a 40 mg/day dose, an “ace inhibitor” blood pressure medication at 20 mg/day, and low-dose aspirin.  This treatment prevented approximately 1,271 heart attacks and stroke in the first year of follow up.

What does CPC recommend?

Many doctors will often start patients at low doses of drugs and gradually increase them to find the proper dose that works for the individual.  However, patients who don’t see improvement in their blood pressure or cholesterol may instead quit taking the medications.  In this study, a combination of medications started simultaneously proves to be an effective, inexpensive strategy to prevent heart attack and stroke in people who are at high risk.

Heart attack and stroke are the leading causes of death in Americans, and these events often occur unexpectedly.  To protect yourself against heart attack and stroke, you rx cialis low price do not have to take expensive, name-brand drugs.  These medications can each cost as little as $4 per month in generic forms.  Take your medications regularly and without exception to get the greatest benefit.  In addition to preventing heart attack and stroke in people who are at high risk, these medications can prevent a first heart attack or stroke.  Talk to your doctor to see if these medications could help you live a healthier life.

This study was published in the American buy generic drugs Journal of Managed Care, 2009 Oct 1.

Information submitted by Lisa Jensen, Colorado Prevention Center


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